The Best Meatloaf Recipe
If you have ever wondered how to make a comforting, juicy, and flavorful meatloaf that will become the star of any dinner table, look no further. This recipe for The Best Meatloaf brings together simple ingredients that harmonize perfectly, creating a tender, savory dish topped with a tangy glaze that everyone will rave about. Whether it’s a cozy family meal or something you want to impress guests with, this meatloaf delivers classic goodness with every bite.

Ingredients You’ll Need
These ingredients are straightforward but essential, each playing a role in creating the rich taste, moist texture, and inviting color of The Best Meatloaf. From the perfect blend of seasonings to the soft breadcrumbs and savory glaze, every element is a building block for success.
- 2 lbs ground beef (85% or 80% lean): The foundation of the meatloaf that ensures juiciness without excess fat.
- 1 medium onion (1 cup, finely chopped): Adds sweetness and depth when sautéed gently before mixing in.
- 1 tsp olive oil: Helps soften the onions for that tender, caramelized flavor.
- 2 large eggs: Act as the perfect binder to hold all ingredients together firmly.
- 3 garlic cloves (minced): Infuses the meatloaf with a subtle savory kick.
- 2 Tbsp ketchup: Incorporated inside for moisture and a touch of tanginess.
- 3 Tbsp fresh parsley (finely chopped): Brightens the dish with fresh herbal notes.
- 3/4 cup Panko breadcrumbs (or gluten-free bread crumbs): Keeps the texture light and tender.
- 1/3 cup milk: Adds moisture and softens the breadcrumbs for a smooth bite.
- 1 tsp salt (or to taste): Enhances all the flavors beautifully.
- 1 tsp Italian seasoning: Brings an aromatic blend of herbs for extra complexity.
- 1/2 tsp ground black pepper: Offers subtle heat and seasoning balance.
- 3/4 cup ketchup (for glaze): Creates a sweet, tangy topping that caramelizes perfectly.
- 1 ½ tsp white vinegar: Adds brightness to the glaze for that perfect zing.
- 2 Tbsp brown sugar: Sweetens and helps the glaze to caramelize.
- 1/2 tsp garlic powder: Deepens the glaze’s savory character.
- 1/2 tsp onion powder: Complements the glaze with mild pungency.
How to Make The Best Meatloaf
Step 1: Prep Your Workspace
Start by lining a rimmed baking sheet with parchment paper or foil—this little step makes cleanup a breeze later. Then, preheat your oven to 350°F to ensure it’s perfectly warm and ready for the meatloaf’s cozy journey to deliciousness.
Step 2: Sauté the Onions
Place a medium skillet over medium heat and add the teaspoon of olive oil. Toss in the finely chopped onion and stir occasionally as they soften and turn golden, about 5 to 7 minutes. This process unlocks their sweetness and brings a deeper flavor to the meatloaf. Once done, set the onions aside to cool, so they mix smoothly without cooking the eggs prematurely.
Step 3: Combine the Meatloaf Mixture
In a large bowl, gather all the ingredients for the meatloaf—ground beef, cooled onions, eggs, minced garlic, ketchup, parsley, breadcrumbs, milk, salt, Italian seasoning, and pepper. Your hands are the best tool here; mix just until everything is well blended but not overworked. This gentle approach keeps the loaf tender, not dense.
Step 4: Shape and Bake
Transfer the meat mixture onto your prepared baking sheet. Shape it into a loaf approximately 8 inches long, 4 inches wide, and 3 inches tall—a classic form for even cooking and impressive presentation. Bake uncovered for 40 minutes at 350°F. This first bake helps the loaf to set and start developing a flavorful crust.
Step 5: Prepare the Glaze
While the meatloaf bakes, whisk together the ketchup, white vinegar, brown sugar, garlic powder, and onion powder in a small bowl. This glaze adds a sweet tangy finish that will caramelize beautifully under the heat.
Step 6: Add the Glaze and Finish Baking
Once the initial bake is complete, spread the glaze evenly over the top of the meatloaf. Return it to the oven for another 20 minutes or until the internal temperature reaches 160°F on an instant-read thermometer. Let the meatloaf rest for 10 to 15 minutes afterward—this step is crucial for juicy, easy slicing.
How to Serve The Best Meatloaf

Garnishes
Simple garnishes such as freshly chopped parsley or a sprinkle of cracked black pepper make The Best Meatloaf look inviting and add a pop of color. For extra flair, consider a few sprigs of thyme or a dusting of smoked paprika on the glaze to boost aroma and visual appeal.
Side Dishes
Meatloaf pairs wonderfully with classic sides like creamy mashed potatoes, roasted veggies, or buttery green beans. For a fresh contrast, a crisp salad dressed with lemon vinaigrette or simple coleslaw brightens the plate and balances the richness of the meat.
Creative Ways to Present
For a dinner party, slice The Best Meatloaf and arrange on a serving platter alongside colorful roasted vegetables or a rustic grain salad. You can also transform leftovers into slider sandwiches with a dollop of mustard or your favorite sauce—meatloaf sliders make crowd-pleasing snacks or casual lunches.
Make Ahead and Storage
Storing Leftovers
Wrap any leftover meatloaf tightly in plastic wrap or store in an airtight container in the refrigerator. It will keep well for up to 4 days, making it a perfect candidate for quick lunches or easy dinners during your busy week.
Freezing
You can freeze leftover meatloaf slices or the entire loaf before glazing. Wrap securely in plastic wrap and foil or use a freezer-safe container. For the best quality, consume within 3 months. When ready, thaw overnight in the fridge for easy reheating.
Reheating
Reheat leftovers gently in the oven at 325°F wrapped in foil to maintain moisture, or warm slices in the microwave covered with a damp paper towel. Avoid overcooking to keep The Best Meatloaf tender and juicy.
FAQs
Can I use a different type of meat for The Best Meatloaf?
Absolutely! While ground beef is traditional, mixing in ground pork or turkey can add different flavors and textures. Just keep an eye on moisture levels as leaner meats may need a bit more binding or fat to stay juicy.
What if I don’t have Panko breadcrumbs?
Regular breadcrumbs work just fine, but Panko adds a lighter texture. You can also use crushed crackers or oats in a pinch. Just ensure the amount stays the same to keep the loaf from becoming too dense.
Is there a gluten-free option for this recipe?
Yes! Simply substitute gluten-free breadcrumbs for the Panko and ensure your ketchup and seasonings are gluten-free. The rest of the ingredients are naturally gluten-free, allowing everyone to enjoy The Best Meatloaf safely.
How do I know when the meatloaf is done?
The most reliable method is using an instant-read thermometer inserted into the center. The internal temperature should reach 160°F. This ensures the meat is cooked safely while staying moist and tender.
Can I prepare The Best Meatloaf in advance?
Definitely! You can mix the ingredients a day ahead, shape the loaf, and keep it covered in the fridge. Then simply bake when you’re ready. This strategy is a great time saver for busy evenings or entertaining.
Final Thoughts
I can’t encourage you enough to give The Best Meatloaf a try. It’s such a satisfying, homey dish that fills your kitchen with irresistible aromas and your plate with classic comfort. The combination of simple ingredients, that luscious glaze, and the ease of this recipe make it a reliable favorite to turn to again and again. Get ready to make dinner something truly special!
PrintThe Best Meatloaf Recipe
A classic and moist meatloaf recipe featuring ground beef, sautéed onions, and a flavorful glaze made from ketchup, vinegar, and brown sugar. Perfectly seasoned with Italian herbs and spices, this meatloaf is easy to prepare and delivers comforting, home-style goodness.
- Prep Time: 15 minutes
- Cook Time: 1 hour
- Total Time: 1 hour 15 minutes
- Yield: 6 to 8 servings 1x
- Category: Main Course
- Method: Baking
- Cuisine: American
- Diet: Halal
Ingredients
Meatloaf Mixture
- 2 lbs ground beef (85% or 80% lean)
- 1 medium onion (1 cup), finely chopped
- 1 tsp olive oil
- 2 large eggs
- 3 garlic cloves, minced
- 2 Tbsp ketchup
- 3 Tbsp fresh parsley, finely chopped
- 3/4 cup Panko breadcrumbs (or gluten-free breadcrumbs)
- 1/3 cup milk
- 1 tsp salt (or to taste)
- 1 tsp Italian seasoning
- 1/2 tsp ground black pepper
Glaze Sauce
- 3/4 cup ketchup
- 1 ½ tsp white vinegar
- 2 Tbsp brown sugar
- 1/2 tsp garlic powder
- 1/2 tsp onion powder
Instructions
- Prep – Line a rimmed baking sheet with parchment paper or foil for easier cleanup, and preheat your oven to 350°F (175°C).
- Sauté Onions – Heat a medium skillet over medium heat and add 1 tsp olive oil. Add the finely chopped onion and sauté, stirring occasionally, until soft and golden brown, about 5 to 7 minutes. Remove from heat and transfer to a plate to cool.
- Make the Meatloaf Mixture – In a large bowl, combine the ground beef, sautéed onions (cooled), eggs, minced garlic, ketchup, chopped parsley, Panko breadcrumbs, milk, salt, Italian seasoning, and black pepper. Use your hands (wear gloves if preferred) to mix gently until all ingredients are just combined without overmixing.
- Shape Meatloaf and Bake – Transfer the meat mixture to the prepared baking sheet and shape it into a loaf approximately 8 inches long, 4 inches wide, and 3 inches tall. Bake uncovered at 350°F for 40 minutes.
- Make the Sauce – While the meatloaf bakes, prepare the glaze by mixing ketchup, white vinegar, brown sugar, garlic powder, and onion powder in a small bowl until well combined.
- Add the Glaze – After the initial 40 minutes of baking, remove the meatloaf from the oven and spread the prepared sauce evenly over the top. Return the meatloaf to the oven and bake for an additional 20 minutes, or until the internal temperature reaches 160°F as measured by an instant-read thermometer.
- Rest and Serve – Remove the meatloaf from the oven and let it rest for 10 to 15 minutes before slicing. This resting period helps the meatloaf set and makes for easier, cleaner slices.
Notes
- Use gloves when mixing the meatloaf mixture to keep hands clean and to mix more evenly.
- If preferred, substitute Panko with gluten-free breadcrumbs to make the recipe gluten-free.
- Check the internal temperature of the meatloaf with a thermometer to ensure it reaches a safe 160°F before serving.
- Letting the meatloaf rest before slicing helps juices redistribute and prevents crumbling.
- Leftover meatloaf can be stored in the refrigerator for up to 3 days and reheated.
Nutrition
- Serving Size: 1 slice (about 1/8th of loaf)
- Calories: 380 kcal
- Sugar: 8 g
- Sodium: 520 mg
- Fat: 22 g
- Saturated Fat: 9 g
- Unsaturated Fat: 11 g
- Trans Fat: 0.5 g
- Carbohydrates: 20 g
- Fiber: 1 g
- Protein: 28 g
- Cholesterol: 120 mg
Keywords: meatloaf recipe, classic meatloaf, easy meatloaf, baked meatloaf, ground beef meatloaf